PSYB64H3 Chapter Notes - Chapter 10: Testis Determining Factor, Chromosome Abnormality, Fallopian Tube

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Sexual development: aristotle argued that the sex of a child was the result of the temperature of semen at the time of conception, hot semen resulted in males, and cool semen resulted in females. In the female fetus, no additional hormones are needed for development. Unlike the testes, the ovaries are not active during fetal development: in the absence of any androgens or anti-m llerian hormone, the m llerian system will develop in the typical female direction. Nonfunctional remnants of the wolffian system remain throughout a woman"s life: androgen insensitivity syndrome (ais) disrupts the normal development of the wolffian system in males, a defective gene produces abnormal androgen receptors . As a result, the fetus"s tissues are blind to the presence of androgens: fetuses with ais have an xy genotype and normal testes. Development of the external genitalia: the development of the external genitalia follows the differentiation of the gonads during the sixth week after conception.

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