PSYC62H3 Chapter Notes - Chapter 13: Orbitofrontal Cortex, Boxed Warning, Peripheral Nervous System
Document Summary
Psyc62 chapter 13: treatments for depression and bipolar disorder. Monoamine hypothesis of depression: hypothesis stating that a monoamine neurotransmitter deficiency causes depressive mood- developed because of reserpine actions and early. Iproniazid became known as the first clinically used antidepressant drug among the mao inhibitors. Mao inhibitors: produce antidepressant effects by binding to mao and preventing it from breaking down monoamine neurotransmitters: mao inhibitor may bind irreversibly or reversibly to mao. Irreversible mao inhibitors: antidepressant drugs that irreversibly inhibit mao: to make up for the loss of functional mao enzymes, neurons synthesize more mao. 1 adrenoceptors: modern mao inhibitors reduce, but do not eliminate, the risk of a cheese reaction first type of modern mao inhibitors were selective inhibitors of maob- greater affinity for maob than. Selective serotonin reuptake inhibitors (ssris: first was zimelidine, withdrawn because it damaged myelin sheathing, found prozac- one of the most prescribed drugs in history.
