PSYD35H3 Chapter Notes - Chapter 3: Basal Ganglia, Chemical Synapse, Substantia Nigra
Document Summary
Psyd35- a primer of drug action, 12th edition. Spinal cord: carry sensory info from body to brain. Brain stem: medulla, pons midbrain (sleep/wake, bp, heart rate, breathing, intestinal functioning) Subthalamus: together with substantia nigra, and basal ganglia constitute the motor system of extrapyramidal system. Basal ganglia: caudate, putamen, goblus pallidus---pd patients have deficiency in da which is located in sn and released onto bg. Hypothalamus: ans control, sleep, eat, drinking, hormones, water balance, emotion. Limbic system: amygdala and hippocampus (reward, beh, emotion, memory) Dopamine rich reward centers: vta, mfb, nucleus acumens located in hypothalamic/limbic areas. Axon varies in length from short as few mm to long as meter. Synaptic plasticity: reshaping and remodeling of neurons. Mitochondria are located in body, fibers, and terminals. Presynaptic terminal onsiste of vesicles that contain different nt (first messengers) Exocytosis: influx in ca ions cause vesicles to fuse with membrane and nt are released into left.
