PSYB64H3 Chapter Notes - Chapter 3: Neurofibrillary Tangle, Axon Hillock, Axon Terminal
Document Summary
100s die each year bc it blocks aps (specifically, blocks na ion movement) 1 : 10-50 = neuron: glia ratio. Membrane: double phospholipid (fatty phosphate-containing molecs) layer, 2 main types of embedded proteins. Na-k pumps: maintain diffs in chem. comp btwn intra and extra, prisoner exchange of sending 3 na out: 2 k in, costs a lot of energy (20-40% of energy req"d by brain) Ca pumps: only ca out, release of neurotrans depends on low levels on intra ca. Cytoskeleton: maintains shape of neuron, filaments x 3: Move various materials within cells: anterograde (= forward) transport: soma axon terminal, retrograde (= backward) transport: axon terminal soma. Alzheimer"s: memory loss, cog + physical decline, death, neurofibrillary tangles consisting of tau protein bc high tau lvls. Beta amyloid = specific type that works with tau to break apart microtubules. Change shape and length of branches during dev and for learning. Soma: nucleus: contains dna, directs cell fxns.
