Textbook Notes (367,747)
Canada (161,363)
Psychology (9,685)
PSYB65H3 (479)
Ted Petit (185)
Chapter 16

Chapter 16 - Detailed Notes

4 Pages
Unlock Document

Ted Petit

Chapter 16Recovery of FunctionNeural Degeneration Regeneration and ReorganizationDegenerationFunction and utility of autopsyprovides insight into how diseases affect human beings along with insight into how person diedTwo ways in which neuronscells dieNecrosisOverwhelming failure to maintain homeostasis within neuronhomicideApoptosisProgrammed cell deathsuicideNecrosisNeurons completely lose their ability to regulate their internal envtSwelling of membranebursting lysisNeurons contents spill out into extracellular fluiddeath of neuronAssociate with rapid damagePossible causesTumors blows to the head infenction ischemiaCan also follow damage that is slow and progressivedamage to secondary areas due to stroke or neurodegenerative diseases Huntingtons choreaCommon causes1 IschemiaIschemia disruption in blood flow that results from a stoke or CVADisrupt energy pathwaysChanges in ion channel concentration ATPReduces production of ATPessential to sodiumpotassium pumpInability to regulate these levels after action potentialIn turn affects watercalcium high concentrations of water leading to swelling1 Acquired InjuryFrom traumatic brain injury TBIGlutmateAlterations in glutamate release Excitotoxicitythe ability of specific compounds such as glutamate to both excite neurons and kill themPrimary neural deathdeath of neurons that occurs immediately after traumawhen glutamate is released in excessleading to a cascade of eventsSecondary neural deathdeath of neurons as a result of calcium influx due to glutamate increase from primary neural deathMain reasons for NecrosisChanges in the ability of the neuron to produce energy ATPDamage to the organelles of the neuron mitochondiaChanges in intracellular concentrations of ions such as calciumApoptosisPart of normal developmentCharacterizedby dead cells in which the nucleus in condensed into a tangle of DNA fragments as well as intact membranesProcess of apoptis is regulated by genes which trigger proteins known as caspases that are responsible for the destruction of the neuronCharacteristic of a number of diseasesParkinsons Huntingtons Alzheimers MS etc
More Less

Related notes for PSYB65H3

Log In


Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.