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PSYC62H3 (313)

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Suzanne Erb

Drugs and the brain For the midterm: chapters 2-6 Except: Chapter 3: “Implications of pharmacokinetics in the fetus and neonate”; Pharmacogenetic and ethinic factors in drug action” Chapter 5: “Chemical neuroanatomy and neurotransmitter distribution” (i.e., you are not responsible for p. 91-100 of Chapter 5). Chapter 6: “Context-Specific tolerance and sensitization” (you only need to understand this section at the level I cover it in lecture); in addition, you are not responsible for p. 122-131 . After the midterm: chapters 7, 10, 12, 13 Except: Chapter 7: “Drug Treatment of Parkinson’s Disease” (p. 172) Chapter 10: “Inhalants: Anesthetic gases and solvents” (p. 259); “Sedative hypnotics and insomnia” (p. 270); “Drug treatment of epilepsy: Anticonvulsant drugs” (p. 272) Chapter 13: “Dissociative Anesthetics: Phencyclidine and ketamine” (p. 347) through to the end of the chapter (i.e., you are not responsible for 347-355). Chapter 2: drug classification and behavioural assessment Drug classifications based upon behavioural or therapeutic actions -describe a drug as belonging to a particular class or type based upon the psychological effect produced or the desired therapeutic action -the new drug shares a profile of effects with other drugs that already belong to that class -drugs classified as ‘major stimulants’=share a set of properties, including actions such as enhancing attention and increasing various types of motor activities ‘antipsychotic’-‘treats’ symptoms of schizo (hallucinations, delusions) useful for treating mania ‘antidepressants’-sometimes used to treat anxiety Drugs labelled ‘atypical’-show an unusual preclinical or clinical profile ie. Clozapine, buspirone -some drugs that exert actions that cross several categories but do not fit into 1 category; ex: weed-has some properties of a sedative-hypnotic, a stimulant, and a mild hallucinogen -in humans the therapeutic effects of drugs often area assessed by rating scales that attempt to measure the symptoms of a particular disorder Ex. Hamilton depression rating scale/beck depression inventory-used to assess the effects of antidepressant drugs, -vs, Hamilton anxiety scale-used to
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