Textbook Notes (368,408)
Canada (161,869)
Psychology (9,695)
PSYC62H3 (313)
Chapter 3

PSYC62 Drugs - Ch3

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Suzanne Erb

Chapter 3Pharmacokinetics pharmacokineticsdynamic processes involved in the movement of drugs within biological systems with respect to the drugs absorption distribution binding or localization in tissues metabolic alterations and excretion from the body what the body does to the drugDrug Absorption lipid solubilityor lipophilicitycapability of being dissolved in fat oilwater partition coefficientthe drug concentration in the oil is divided by its concentration in the water the greater the coefficient the more easily the drug molecule can passively penetrate a membrane if other factors are held constanttwo imp factors in a drugs effects are its concentration and its rate of accumulation at sites of actionthese are dependent on its concentration in the blood plasmawhich is dependent on the drugs access to the blood which is heavily influenced by the route of administration Routes of Administration most common route is thru the mouth per cos or PO so its absorbed in various parts of the GI tractsmall intestine safe and cheap the higher the concentration of the drug the easier it is for the drug to diffuse passively across the intestinalcell membranesoral route is the safest way to administer drugs but it has di
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