Textbook Notes (367,969)
Canada (161,538)
Psychology (9,695)
PSYC62H3 (313)
Chapter 2

Chapter 2

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Suzanne Erb

Drugs and the Brain Chapter 2 Basic Principles of Psychopharmacology What is a drug? A non-food chemical that alters one or more biological processes excluding substances used for nutrition purposes such as salt, water, vitamins, etc known as an exogenous substance also does not include chemicals originating or produced within an organism that are used to carry out normal biological functioning known as endogenous substances Factors that determine drugs effect concentration of the drug at its site of action rate of accumulation dose: quantity of drug administered at one time dosage: administration of drug per unit of time Drugs and Receptors pharmacodynamics biochemical and physiological effects of drugs and their mechanisms of action receptors -very specific sites all throughout the body where the vast majority of drugs act -site is comprised of very large molecules, usually proteins - when ligand binds to receptor, receptor becomes activated ligand -biologically active chemicals of the body induce the effects of proteins at receptor sites -include hormones, neurotransmitters, neurohormones and neuromodulators -when it occupies receptor, it is a bound ligand www.notesolution.com
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