PSYC62H3 Chapter Notes - Chapter 5: Neurotransmitter, Synaptic Plasticity, Neuromodulation
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Chapter 5: synaptic transmission, drugs, and chemical neuroanatomy. Neurotransmitters and chemical signaling in the nervous system. The same substance can meet the definition of a neurohormone, neuromodulator, and neurotransmitter (eg. da) Most substances that are neurotransmitters also act as neuromodulator. Dale"s law or dale"s principal a given neuron uses the same neurotransmitter at all its synapses. Thus, a given neuron can be identified in terms of which transmitter it uses (ie. a. This observation was first formulated based upon early studies of classical studies of classical transmittesr, but it sometimes has been misinterpreted to mean that one neuron uses only one transmitter. We now know that a given neuron can co-localize multiple transmitters - often a combo of a classical transmitter and a neuropeptide. It"s not true that any given neuron can have any combo of transmitters. Monoamines (ma) includes the catecholamines da, ne, and epi, as well as the indolamine 5-
