PSYC62H3 Chapter Notes - Chapter 13: Points Of The Compass, Chemotherapy, Grey Matter
Document Summary
Dissociative anaesthetics, psychedelics, and hallucinogens chapter 13 notes. P/p/hs (psychotomimetic/psychedelic/hallucinogenic substances: aboriginals used p/p/hs (iboga, mescaline, psilocybin) containing plants in rituals, healing, and promote group cohesiveness. 1960"s: psychotherapists recommend using these drugs for mental illness. Monoamine-related subs: effects are mediated by differences in activity of seretonin (5ht), da, and ne in cns. Cannabiniods: derivatives of marijuana plant (or similar synthetics) It may cause a dysphoric reaction (panic/paranoid) in some cases: nonhumans won"t self-administer many p/p/hs in their pure form, whereas they will with psychotics/sedative-hypnotics, and narcotics. When pure lsd/mescaline used in catheter, animals avoid administering: three types of p/p/hs are readily administered by nonhumans: delta 9thc (in marijuana), Animals are trained to tell difference b/w the effects of a placebo and those produced by particular drug. E. g. , rat conditioned to respond to lever if injected with placebo, and again if injected with lsd. Rats learn to respond to correct lever and is rewarded with a drug that mimics.
