PSYC62H3 Chapter 3: Chapter 3 Textbook Notes
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pharmacodynamics was concerned w/ what the drug does to the body but pharmacokinetics is concerned w/ what the body does to the drug. the dynamic processes involved in the movement of drugs within biological systems w/ respect to the drug"s absorption, distribution, binding or localization in tissues, metabolic alterations and excretion from the body. this is what determines the difference btwn 2 drugs" potency. depends on species, age, ethnicity, genetics, psychological status, physiological status, maybe gender. 2 important factors in a drug"s affects are it"s rate of accumulation and concentration. drugs must enter the cns to produce its" psychological effects but drug molecules are just too large to cross membranes. so drugs must be soluble in fat! drug"s capability of being dissolved in fat. most important factor in a drug"s ability to pass through membranes.