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1 Dec 2016
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BIO120H1 Full Course Notes
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BIO120H1 Full Course Notes
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Proteins, constitutes most of the cells dry mass, biomedical importance of proteins. They are the main structural components of the cytoskeleton. Proteins known as immunoglobulin serves as the first line of defense against bacteria. Some proteins act as receptors, others are transporters, for storage, and as respiratory pigments: a protein molecule is made from a long un branched chain of amino acid, each linked to its neighbor through a covalent peptide bond. Hydrogen bonds: between polar side chain of amino acids. Electrostatic interactions: between oppositely charged polar side chain of amino acids. Van der waal forces: between nonpolar side chains. Disulfide bonds: s-s between sh group of cysteine residue. Structural organization of proteins: primary structure: is the linear sequence of amino acids help together by peptide bond, secondary structure: the peptide thus formed assume a 3- dimensional structure by folding into a helical, linear or mixed form. The most common folding patterns are helix and b-pleated sheets.

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