BIO130H1 Chapter : Pg. 1071-1080.docx

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10 Apr 2012

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BIO130H1 Full Course Notes

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5 stages of mitosis: protophase, prometaphase, metaphase, anaphase and telophase. M-cdk drives early stage of mitosis; accessory of mitotic spindle to ensure that sister chromatin and chromosome condensation. Dephosphorlyation activates m-cdk at the onset of mitosis. Long dna molecule are pulled together at the end of s phase. Interpolar microtubule: plus end interact with each other. Mitotic spindle: array of microtubules that separate the sister chromatins. Kinetochore microtubule: are attached to the sister chromosome. Microtubule-dependent motor proteins govern spindle assembly and function. 4 types of motor protein: kinesin-5, kinesin-14, kinesin-4 and 10 and dynesin. Kinesin-5 contains 2 motor domain interact with the plus end. Kinesin-14 contains single motor: minus end directed. Kinesin-4 and 10 are plus end directed. Two mechanisms collaborate in the assembly of a bipolar mitotic spindle. Two spindles and plus ends interacting with each other. Centrosome duplicates occurs early in the cell cycle.

Related Questions

What would likely happen if sister chromatids separated beforekinetochore microtubules where attached to the chromosomes in ahuman skin cell? Mitosis would start over Mitotic spindle wouldcollapse Prophase would not be completed Daughter cells wouldlikely have aneuploidy Cell plate formation would be disrupted

periwinklefox543

Select all of the following statements that typically occur during anaphase:

_____________________

Sister chromatids are copied and separate into separate chromosomes.

The non-kinetochore microtubules elongate.

Condensin proteins assist with separation of the chromatids.

The kinetochore microtubules shorten.

Cohesin proteins are degraded.

Cytokinesis of animal cells is characterized by the appearance of a cleavage furrow. When does the cleavage furrow first start to appear?

_____________________

1-The five stages of mitosis occur in which order?

	A- Anaphase, prometaphase, metaphase, telophase, prophase
	B- Prophase, prometaphase, metaphase, anaphase, telophase
	C- Telophase, anaphase, prophase, prometaphase, metaphase
	D-Prophase, metaphase, prometaphase, telophase, anaphase
	E- Anaphase, telophase, prometaphase, metaphase, prophase

2- Select all of the following that are true of linkedgenes.

	A- They are used in gene mapping
	B - They are likely to be inherited together
	C- They can be used to identify genes with mutations that areresponsible for disease
	D- They are likely to be close together on the samechromosome

3- Select all of the following that occur during anaphase

	A- Astral microtubules polymerize (net)
	B- Chromosolal microtubules polymerize (net)
	C- Chromosomal microtubles depolymerize (net)
	D- Polar microtubules polymerize (net)
	E- Polar microtubules depolymerize (net)

4- Select all of the following that require protein involvementin transporting a solute across the plasma membrane.

	A- Simple diffusion
	B- Active transport
	C- Facilitated diffusion
	E- Osmosis

5- Select all of the following that can trigger different typesof channels to open, thereby allowing passage of ions across themembrane.

	A- Ligand binding
	B- Change in membrane voltage/potentials
	C- A physical stress on the channel

azuresnake426

BIO130H1 Chapter : Pg. 1071-1080.docx

BIO130H1 Full Course Notes

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