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HomeTextbook Notes300,000CA170,000

CSB332H1 Chapter 6: Chapter 6 Notes

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coppercattle724
17 Jan 2012
School
UTSG
Department
Cell and Systems Biology
Course
CSB332H1
Professor
Melanie Woodin

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Document Summary

Ionic basis of the resting potential: at rest neuron (-) wrt outside, high k inside, low na & cl inside grads. Membrane pot stops them from moving w conc: changing outside k changes k eqm pot changes membrane pot. Whereas is change outside cl equivalent change in inner cl cl eqm pot & membrane pot unchanged. Passive: at rest na constantly moves into cell recuding membrane (-) k no longer in eqm k leaks out. If no compensation then changes in inner k & na. Active: compensated by na-k pump (3na out, 2k in) Overall transports more (+) out contributes several mv to membrane pot: resting membrane pot depends on: Relative permeability of membrane to na & k. Pump ratio: cl permeability important for electrical stability, cl eqm pot can be (+) or (-) wrt resting membrane pot (depends on cl transport processes) Plays little role in resting membrane pot.

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Related Questions

Which of the following statements about resting membrane potential is not true? Why?

(a) The resting membrane potential for most animal cells is 0 mV, because the positive and negative ions are in balance.

(b) The resting membrane potential for most animal cells is positive, because Na+ ions are so plentiful inside cells.

(c) The resting membrane potential for most animal cells is negative, because the inside of the cell is more negatively charged than the outside of the cell.

(d) At the resting membrane potential, no ions enter or exit the cell.

In order for Neurons to communicate, Resting Membrane Potential must CHANGE. Examples of changes in Membrane Potential included Graded Potentials and Action Potentials. In order for there to be a change in membrane potential, ions must move across the plasma membrane. There are THREE Primary types of Ion Channels: Passive (Leak) Channels, Voltage-gated Channels and Chemically-gated Channels.

DIRECTIONS

Select ONE type of Ion Channel and indicate whether that Ion Channel is MOST important for producing Resting Membrane Potential, Graded Potentials or Action Potentials. Provide detailed support for your choice.

In order for Neurons to communicate, Resting Membrane Potential must CHANGE. Examples of changes in Membrane Potential included Graded Potentials and Action Potentials. In order for there to be a change in membrane potential, ions must move across the plasma membrane. There are THREE Primary types of Ion Channels: Passive (Leak) Channels, Voltage-gated Channels and Chemically-gated Channels.

DIRECTIONS

Indicate which voltage-gated channels are functioning during each phase of an Action Potential