CHM138H1 Chapter all: Substitution Reactions

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1 Dec 2016
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CHM136H1 Full Course Notes
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Substitution reaction involves the exchange of a functional group of a chemical compound to another group. The electrophile in a substitution reaction is called the substrate which contains the leaving group. The leaving group releases electron density through induction which makes the adjacent carbon atom electrophilic. The leaving group stabilizes negative charges that may develop from substitution reactions. The group that replaces the leaving group is called the nucleophile. Organic compounds with a halogen subgroup are usually used as substrates in a substitution reaction. These halogenated organic compounds are also called organohalides. Naming halogenated organic compounds in iupac nomenclature applies the same process as in naming alkanes: identify the name of the parent, identify the name of the substituents. Halogen subgroups have names such as bromo-, fluoro-, chloro-, and iodo-: assign locants to each substituent, name the compound with its substituent alphabetically-arranged. The carbons of alkyl halides are denoted by alpha and beta positions.

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