HMB265H1 Chapter Notes - Chapter 13: Human Height, Heritability, Phenotype
29 Oct 2017
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HMB265H1 Full Course Notes
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Hmb265 lecture 13 readings - quantitative trait analysis. = genotypic information doesn"t always show what phenotype is. Variance is a statistical measure of the amount of variation in a population. Quantitative traits: phenotype measured over rand of numbers. Often have bell-shaped normal distribution of phenotypic values. More genes in expression of trait = more possibilities for phenotypic variation. = phenotypes of individuals of one genotype distributed in narrow bell-shape curve. Centered around average phenotype for that genotype. This b/c individuals w/ same genotype subject to slightly different microenvironments. I. e. contribution of genes (not environment) to phenotypic differences. Compare individual in population to average phenotype for population. = average squared difference between each individual value and mean. Genetic variance can be separated from environmental variance. Distinguish environmental from genetic effects on phenotypic variation. Quantify one variable and control for the other. Find effect of environment: plant genetically identical dandelions. Find effect of genotype: plant seeds from different plants in controlled greenhouse.
