HMB440H1 Chapter Notes - Chapter 1: Amyloid, Dementia, Neuroinflammation
Document Summary
Dementia is extremely costly to healthcare, and there is no therapy available to treat the underlying disease process. Wave of dementia is in desperate need of 3 things: Although dementia is probably the costliest disease it is not funded appropriately considering this. The biggest reason dementia is not funded is that there is lack of visibility/advocation for the disease. However, social and political awareness is starting to shed light on the disease impact and funding is increasing slowly - in fact, the budget for ad increased to 1 billion (comapred to 200 million before) Solanezumab is one drug that may have potential to slow cognitive decline and lends credence to the amyloid hypothesis: build of amyloid- in the brain is one of the triggers of alzheimer"s disease. There is a growing interest in early interventions that can clear aberrant proteins. However, some researchers claim even if you remove these proteins dead brain cells remain dead o.
