HMB265H1 Chapter Notes -Alkaptonuria, Aspergillus, Western Blot

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2 Oct 2013
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HMB265H1 Full Course Notes
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HMB265H1 Full Course Notes
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Genetics: molecular genetics: works on few genes at a time, genomics: study of the complete gene set (genome) Continuum of genetic and environmental factors contributing to disease: it"s a gradient. Chromosomes are hypothesized to hold information because they are passed down intact to a new generation through very precise divisions. Diploid: two sets of the genome, 2 identical chromosome sets ex: humans. Haploid: one set (the haploid number is n = number of chromosomes in a set) ex: fungi, bread mold. Homologs/homologous chromosomes: two identical chromosomes (paired in meiosis) can be different alleles. Not necessarily next to each other when not undergoing meiosis. Centromere: constricted region acting as attachment point to move the chromosomes around. Telomere: tips of the chromosome work like the aglet. Proteins: structural: contribute to outward physical structure hair, nails, muscles, cytoskeleton, enzymatic: catalyze the reactions within the cells, regulatory: turn gene activity on and off.

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