Ethics left behind as drug trials soar in developing countries. In 2008, there were three times as many developing countries participating in clinical trials registered with the us fda than there were between 1948 and 2000, with many countries such as. Challenging assumptions about minority participation in us clinical research. Here, participants may derive benefits o the third requires a large number of volunteers with the targeted disease. These studies measure efficacy of an investigational treatment and sometimes a comparative benefit. Americans are more likely to be mistrustful than whites. Physician bias, false perceptions, and prejudices may also dictate the lower number of minority participants in trials. Physicians may be less likely to prescribe certain treatments to their minority patients. Some biases may lead physicians to have more negative impressions of their african american patients than of their white patients. Individuals of diverse ethnic and racial backgrounds should have the opportunity to participate in clinical trials.