PSL201Y1 Chapter Notes -Hypercalcaemia, Tubular Fluid, Hypotension
Document Summary
Ca triggers exocytosis of chemical messengers, stimulates secretion of substances, stimulates muscle contractions, and increases the contractility of the heart and blood vessels. Hypercalcemia results with muscle weakness, atrophy, lethargy, behavioral changes, hypertension, sontipatino, and nausea. Hypocalcemia causes numbness and tingling sensations, muscle cramps and spasms, exaggerated reflexes and hypotension. Ca can be added to the plasma from bone and absorbed via the digestive tract. It can be removed from the plasma by bone and the kidneys. The bone provides a reservoir of ca through resorption. When plasma ca levels are high, ca can be deposited into bone. Ca is transported in blood by carrier proteins or is free in the plasma. Ca that is free in the plasma is freely filtered at the glomerulus. 99% of filtered ca is reabsorbed as the tubular fluid moves through the renal tubules.
