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PSL201 – Feb 14 – Endocrine 2 Hypothalamus and Pituitary Gland.docx

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University of Toronto St. George
Michelle French

PSL201Feb 14Endocrine 2 Hypothalamus and Pituitary GlandThe Endocrine System Endocrine Glands and Hormone Actionstwo types of endocrine glands o primary endocrine organs secrete hormones o secondary endocrine organssecretion of hormone is secondary to some other functionPrimary Endocrine OrgansHypothalamus and Pituitary Glandregulate virtually every body systemhypothalamus secretes hormones which affect the pituitary glandpituitary gland connected to hypothalamus two parts posterior lobe and anterior lobe Neural Connection Between Hypothalamus and Posterior Pituitaryneural endings in post Pituitary secrete ADH and oxytocin neurohormonesADH synthesized in the paraventicular nucleus and lesser in the supraoptic nucleusOxytocin synthesized in supraoptic nucleus and lesser in paraventicular nucleusAfter synthesis they are packed into vesicles and transported to axon terminals in the post PituitaryReleased into blood by exocytosis when signal is received Blood Connection Between Hypothalamus and Anterior Pituitaryanterior lobe secretes trophic hormones hormones that regulate secretion of other hormones o can be a stimulating hormone or a inhibiting hormone Anatomy of HypothalamicPituitary Portal Systemhypothalamicpituitary portal systemo connects anterior lobe and hypothalamus o arrangement of blood vessels o when the hypothalamus secretes hormones they travel down to the anterior lobe Trophic Hormones of the Hypothalamus and Anterior PituitaryProlactin realeasing Hormone PRH stimulates ant pituitary to release prolactin which then stimulates mammary gland development and milk productionProlactin inhibiting hormone PIH inhibits prolactinThyrotropin releasing hormone TRH release of thyroid stimulating hormone TSH from ant pituitary TSH stimulates the secretion of thyroid hormones from the thyroidCorticotropin realeasing hormone CRH release of adrenocorticotrpic hormone ACTH by the ant pituitary ACTH stimulates the secretion of hormones from the adrenal cortexGrowth hormone releasing hormone GHRH release of growth hormone GH from the ant pituitary GH regulates growth and
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