PSY407H1 Chapter Notes - Chapter N/A: Middle Frontal Gyrus, Inferior Frontal Gyrus, Striatum
Document Summary
Common biology of craving across legal and illegal drugs a quantitative. Brain regions that overlapped with drug cue-reactivity were found in the anterior cingulate cortex (acc), ventral striatum, and the right pallidum. They are related to drug cue reactivity, so they have an effect in craving. Addicts are vulnerable to drug use when being exposed to stimuli that is related to previous instances of drug use. Nicotine cue reactive regions: bilateral ventral striatum, acc, left amygdala, and left temporo-parietal junction. Alcohol cue reactive regions: bilateral ventral striatum, left pallidum, right amygdala, left thalamus, right inferior frontal gyrus, and left middle frontal gyrus. Cocaine cue reactivity regions: right ventral striatum, left amygdala, left caudate, acc, right mid-posterior insula, left inferior parietal lobe, posterior cingulate cortex, dorsofrontomedian cortex, right precentral gyrus, and lingual gyrus. All 3 had in common: ventral striatum. Proposed that this region is the core brain region involved in neural responses to drug cue exposure.
