PSY100H1 Chapter Notes - Chapter 9: Prodrug, Nail Polish, Ethylene
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PSY100H1 Full Course Notes
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Ethylene: intoxicating agent that causes delirium, disinhibition, euphoria, and feelings of disembodiment. Gamma-hydroxybutyrate (ghb): substance that serves as both a drug and a neurotransmitter that produces cns depressant effects. White, tasteless powder that dissolves easily in water. Club drug ghb-associated sexual assault referred to as date rape = schedule i controlled substance. Sodium ghb is treatment approved by fda for narcolepsy (excessive daytime sleepiness) schedule iii; sodium oxybate (xyrem) Recreational users obtain ghb from illicit sources or by synthesizing ghb from gamma-butyrolactone (gbl) = schedule i controlled substance: gbl used in household products, such as stains and paint removers, dea exempts products containing <70% of gbl. Ghb and gbl occurs in small amounts in red and white wines, vinegar, beer, and coffee. Gbl serves as prodrug, metabolically converted to ghb in body. Users either underreport ghb abuse or ghb is being used for nonrecreational uses (sexual assaults)