BIOL 3530 Chapter Notes - Chapter 11: Lactose Permease, Electrochemical Gradient, Active Transport

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Charged macromolecules in the cell attract counter ions. To counter this, cells pump out large amounts of ions. Animal cells are negatively charged (negative electrical potential). Electrochemical gradient for a given ion: ion gradient plus membrane electrical potential. 2 forces acting on a ion that is inside or outside of a cell: the charge of the cell. Therefore a negatively charged cell will attract a positively charged positive na ion so it can equalize the ion: ion concentration. High concentration on the outside of na so it wants to go inside the cell. K is also positively charged so it will have the same effect with the charge of the cell however its ion concentration means it wants to leave the cell. Na is very far from its equilibrium k is very close to its equilibrium. The na/k pump transports 3 na+ out while bringing in 2 k+. K+ leak channels allow k+ to leak out.

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