Biochemistry 2280A Chapter Notes - Chapter 14: Lysine, Uracil, Uridine
25 Dec 2016
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Rna functions include: template for proteins, making ribosomes, catalyzing protein synthesis. Rna is made of ribonucleotide monomers and dna is made of deoxyribonucleotide monomers. Each monomer is made of 3 parts; a monosaccharide, a nitrogenous base and a phosphate. Is either ribose sugar (has oh on 2") or deoxyribose (which has an h on 2") Purines are joined to the anomeric carbon (1") of ribose or deoxyribose using a n-glycosidic bond. The anomeric carbon is in the beta configuration. A sugar joined to nitrogenous base is called a nucleoside. The nucleosides are adenosine, guanosine, cytidine, thymidine, uridine. Phosphates are attached to the 5" of the ribose or deoxyribose using a phosphoester linkage. Small d in-front of nucleotide means deoxyribose ex. dttp. Phosphate group on 5" c of one nucleotide from a phosphoester bond with oh at 3" c of another nucleotide. Sequence is always written 5" to 3".
