Biology 2581B Chapter Notes - Chapter 3: Dolichol, Toxoplasma Gondii, Farnesol
29 Mar 2017
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Remnant chloroplast apicoplast - essential for parasite growth and development. Antibiotic-induced loss of the apicoplast in cultured malaria parasites can be chemically rescued by providing isopentenyl-pyrophosphate (ipp) in the medium. Ipp generated by apicoplast resident isoprenoid biosynthesis pathway is apparently the one apicoplast metabolite that parasite cannot live without in red blood cell. Apicomplexan parasites, the dark side of the algal world. Phylum of protists that live as intracellular parasites. Part of a large branch of the eukaryotic tree of life that is now known as the chromalveolates. Through the merger of two eukaryotic cells: a protist host and a red algal endosymbiont. Largely maintained the plastid despite the fact that they are no longer photosynthetic (a few, such as cryptosporidium, have lost the organelle) Chloroplasts in plants have metabolic functions beyond photosynthesis and provide the cell with a number of crucial compounds. Nonphotosynthetic functions of the chloroplast are largely conserved in the apicoplast.
