Biology 1002B Chapter 14.2 + 14.3: Ch. 14.2 + 14.3

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The promoter in operons of prokaryotes are meant to function as a simple way to coordinate the synthesis of related proteins (proteins w/ related functions) In eukaryotes, the coordination to organize proteins w/ related functions is under the control by: Short-term regulation: genes can quickly get turned on/ off, depending on environment (similar to operon regulation) Long- term regulation: regulatory events required for an organism to develop & differentiate; only in multicellular eukaryotes! In eukaryotes, regulation of gene expression occurs at several levels. Regulation of gene is more complicated in eukaryotes since: dna is organized with histones, winded into chromatin, acquire a large number of different cells, nuclear envelops separates transcription and translation. Gene is regulated on multiple levels: transcriptional, post-transcriptional, translational regulation, post-translational regulation. Transcriptional regulation: determines which genes are transcribed, controls initiation rate. Post-transcriptional: determines type/ availability of mrnas to ribosomes, using. Translational: determines rate of translation by controlling rate of initiation of protein synthesis.

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