Health Sciences 1001A/B Chapter Notes - Chapter 16: Coronary Artery Disease, Sidestream Smoke, Coronary Circulation

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Nicotine addiction: tobacco: leaves of cultivated tobacco plants prepared for smoking/chewing, or snuff, nicotine: poisonous, addictive substance in tobacco, responsible for many of effects. Reaches brain via bloodstream seconds after inhaled through membranes of mouth or nose. Low doses: stimulant; increases heart rate, blood pressure. Adults: alertness, concentration, rapid info processing, memory, learning; opposite for teens. Relieves withdrawal symptoms: anxiety, irritability, mild depression. Loss of control: quit: 65% relapse in 3 months, 75% in 6 months, regular: 40 min (routine) Tolerance & withdrawal: withdrawal symptoms: severe cravings, insomnia, confusion, tremors, difficulty concentrating, fatigue, muscle pains, headache, nausea, irritability, anger, depression. Social & psychological factors: secondary reinforcer: stimuli that are not necessarily pleasurable in themselves but are associated w/ other stimuli that are pleasurable. 2: cyp2a6: influences metabolization of nicotine, regulate enzyme, drd2: associated w/ dopamine. Positive attitudes toward tobacco: 70% teens wish they hadn"t started, use in movies=increased by 50% (1998-2000); influences youth- find new persona.

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