Physiology 3120 Chapter Notes -Alkaloid, Phenoxybenzamine, Tubocurarine Chloride

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Consciousness, evoked potential, eeg & sleep: consciousness: awareness of environment & oneself, two components, content of consciousness. Cerebral cortex: memory, perceptions of sensory experience (auditory, visual, somatosensory & vestibular) & attention: level of consciousness. Brainstem reticular formation: awake, alert & sleep. Bilateral lesion of cerebral cortex (ex. decreased oxygen (anoxia), hematoma (blood clot), produces pressure on cortex: decerebration. Person who has a lesion in this area can become decerebrate. No longer an activating system coming from brainstem. Because reticular formation is known to have specific nuclei & pathways with specific neurotransmitters (ne, e, serotonin, dopamine, ach) that have specific functions. Simple view: ascending projections operate by causing depolarization of outer cortical dendrites, descending projection (reticulospinal) send post synaptic inhibition to motorneurons of proximal (postural) muscles during rem sleep. Action potential: put electrodes onto the skull of a person especially in occipital visual cortex, record differences in eeg patterns.

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