Psychology 2220A/B Chapter 5: Chapter 5 - the research methods of biopsychology

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Invasive physiological research methods: stereotaxic surgery: requires use of stereotaxic atlas and instrument. Intracellular unit recording: membrane potential of a neuron: extracellular unit recording: firing of a neuron, multiple unit recording: firing of many neurons. Pharmacological research methods: routes of drug administration, selective chemical lesions. Locating neurotransmitters and receptors in the brain: dye or radioactive labels used to visualize the protein of interest. Immunocytochemistry: based on the binding of labeled protein-specific antibodies. Immune response: antibodies created that bind and remove/destroy antigens (foreign proteins) In situ hybridization uses labeled rna to locate neurons with complementary mrna. Modern approaches to neuropsychological testing: single-test approach: used to differentiate brain damage from functional (psychological) causes, standardized-test-battery approach: same goal as single-test approach e. g. halstead-reitan, customized-test-battery approach: now predominant, characterized nature of psychological deficits. Intelligence: wechsler adult intelligence scale (wais), iq test: memory: digit span subtest.

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