Psychology 2220A/B Chapter Notes - Chapter 5: Transcranial Magnetic Stimulation, Positron Emission Tomography, Cerebral Angiography

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Contrast x-rays- inject something that absorbs x-rays less or more than surrounding tissue. Recording human psychophysiological activity: muscle tension, electomyography is the technique of measuring the electrical activity of muscles, electromyogram (emg) indicates tension of muscles under the skin, eye movement. Invasive physiological research methods: stereotaxic surgery, requires the use of stereotaxic atlas and instrument. Invasive electrophysiological recording methods include the following. Inject animal with radioactive 2-dg and allow it to engage in behavior of interest. Use autoradiography to see where radioactivity accumulated in brain slices. Cerebral dialysis- measures extracellular concentration of speci c chemicals in live animals. Subjects missing a given gene can provide insight into what the gene controls. Dif cult to interpret results- most behaviour is controlled by many genes and removing one gene may alter the expression of others, including compensation for missing gene. Antisense drug block expression of a gene. Green uorescent protein (gsf) exhibits bring green uorescence when exposed to blue light.

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