BI226 Chapter Notes - Chapter 4: Hh Blood Group, Cream Gene, Glycosyltransferase

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11 Apr 2013
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Chapter 4 modification of mendelian ratios: wild type allele. Allele that occurs most frequently in population. Designated as + or wt : mutant allele. Loss of function mutation: null mutation if complete loss of function. Gain of function mutation: usually dominant. Incomplete dominance: when one allele is not completely dominant to another then it is said to show incomplete or partial dominance. The phenotype of the heterozygote is intermediate to those of the homozygotes: classic example: Flower colour in snapdragons: red flowered x white flowered. Palomino horses: incomplete dominance: palominos do not breed true when bred together: Progeny are 1/4 cremellos (extremely light colored), 1/2 palominos and 1/4 light chestnuts. 1:2:1 ratio is characteristic of incomplete dominance: c/c produces a horse that is light chestnut (or sorrel), c/ccr palamino, and ccr/ccr the cremello. Other coat color genes are necessary but are at different loci.

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