PS277 Chapter Notes - Chapter 2: Telomere, Elastin, Sildenafil
Document Summary
Is there enough biological similarity between hibernating mammals and humans to use this as effective evidence? whether the number of calories one eats has an influence on aging. Page 3 controlled experimental evidence with humans is lacking, Okinawans, who eat only 60% of the normal japanese diet, have 40 times as many centenarians. Okinawan incidence of cardiovascular disease, diabetes, and cancer is half that of the rest of. Definiton: cells grown in laboratory culture dishes undergo only a fixed number of divisions before dying, the number of possible divisions dropping depending on the age of the donor organism; hayflick limit. Evidence suggests that the tips of the chromosomes, called telomeres, play a major role telomerase is needed in dna replication to fully replicate the telomeres. telomerase normally is not present in cells, Definiton: free radicals, highly reactive chemicals produced randomly in normal metabolism free radicals may cause cellular damage, in turn impairs the functioning.
