BIOL 1000 Chapter Notes - Chapter 11: Cri Du Chat, X-Inactivation, Testis Determining Factor

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15 Dec 2013
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Genes located on the same chromosome may be inherited together in genetic crosses. Reasoned genes located far apart on chromosome more likely to be separated from each other during meiosis. Females have two copies of xx chromosomes. Males only have one x, and one y chromosomes. Directs development of maleness in early development of embryo. Becomes active after 6-8weeks in xy embryos. Produce proteins that stimulated the development of testes: testes then secrete hormones that start the degeneration of tissue that would turn into female parts. Genes coding breast development, facial hair coded in autosomes. Females inherit genes for penis structure, but do not express them. Sex linkage comes from two differences: males have one x, hence are hemizygous for genes located on x chromosome, females have no alleles located in the y chromosome. Fly: white eye allele located on x chromosome. Females inactivate most of the genes on one x chromosome.

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