BIOL 3155 Chapter Notes - Chapter 12: Internal Ribosome Entry Site, Pestivirus, Flaviviridae
4 May 2020
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Virus structure: small nucleocapsid enclosed in a lipid containing envelope. Concentric layers of density immature form has spikes. *[0 y (19305) focus of chapter 12 controlled by vaccination o. Uses arthropod vectors: via mosquitoes (cid:8869) replicate in these vectors. High fever, muscle pain , headache, vomiting. Latent stage (quiet stage) lever disappears like it"s going away. Most people recover otherwise go to . Repeat of step 1 but more severe. Origin : west nile , africa came to tew world due to slave trade. Infection of uninfected individual with an infected patient serum = transmission. 1 mrna identical to genome rna t - sense ssrna. " coding regions : s" - proximal region in - terminal) Viral rna polymerase : distal 3 " region resemble picornaviruses that have required an envelope. @ 3" end: ires : internal ribosome entry site (cid:8869) directs initiation of viral synthesis. S" methylated- no poly a tall cap at 31 end.
