KINE 1020 Chapter Notes - Chapter 23: High-Density Lipoprotein, Coronary Circulation, Fibrous Cap
28 Jan 2016
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Document Summary
Cardiovascular disease (cvd) are one of the leading causes of death canada. As with most chronic conditions, the risk for cvd is both related to genetic predisposition and lifestyle factors. Cholesterol and triglycerides are circulated in the blood by protein carriers. There are 2 kinds of cholesterol: low density lipoprotein (ldl): linked with atherosclerosis, bad for cvd, high density lipoprotein (hdl): good for cvd. Atherosclerosis is the development of fatty plaques in the blood vessels; these fatty deposits are caused by the high concentrations of ldl in the blood stream. The high concentrations ldl become oxidized by free radicals in the arterial wall and it becomes plaque accumulation. Atherosclerosis leads to the narrowing of the arterial lumen. The platelets cause a fibrous cap over the plaque; this fibrous cap can crack and knock loose a piece of the ldl plaque.
