NATS 1870 Chapter 1: Scholarly_Article
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Lian he1 , yuanwei zhang2 , guolin ma1 , peng tan1 , zhanjun li2, Shengbing zang1, xiang wu2, ji jing1, shaohai fang1, lijuan zhou3, Youjun wang3, yun huang1, patrick g hogan4, gang han2*, yubin zhou1,5* 1institute of biosciences and technology, texas a&m university health science. Center, houston, united states; 2department of biochemistry and molecular. Pharmacology, university of massachusetts medical school, worcester, united. States; 3beijing key laboratory of gene resource and molecular development, College of life sciences, beijing normal university, beijing, china; 4division of. Signaling and gene expression, la jolla institute for allergy and immunology, la. Jolla, united states; 5department of medical physiology, college of medicine, Texas a&m university health science center, temple, united states. Abstract the application of current channelrhodopsin-based optogenetic tools is limited by the lack of strict ion selectivity and the inability to extend the spectra sensitivity into the near-infrared (nir) tissue transmissible range. Here we present an nir-stimulable optogenetic platform (termed.