PSC 432 Chapter Notes - Chapter 37: Pyrantel, Strongyloides Stercoralis, Brugia Malayi

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Anthelmintic drugs: nematodes: diethylcarbamazine, ivermectin, mebendazole, pyrantel pamoate, thiabendazole, trematodes: praziquantel, cestodes: albendazole, niclosamide. It is the drug of choice in the treatment of infections by whipworm (trichuris trichiura), Mebendazole acts by binding to and interfering with the assembly of the parasites . It acts as a depolarizing, neuromuscular blocking agent, causing persistent activation of the. Erythema multiforme and stevens-johnson syndrome which may be fatal: contraindicated during pregnancy, ivermectin. Onchocerca volvulus, and is a first choice drug for cutaneous larva migrans and strongyloides: targets the parasite s glutamate-gated cl channel receptors. Ivermectin is the drug of choice for the treatment of onchocerciasis (river blindness) caused by. Immobilize microfilariae, and render them susceptible to host defense mechanisms. This drug is the agent of choice for the treatment of all forms of schistosomiasis and other: the trematodes (flukes) are leaf-shaped flatworms that are generally characterized by the tissues they infect. Ae; dizziness, malaise, and anorexia, as well as gi upsets.

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