CHE 4341 Chapter Notes - Chapter 3: Ester, Lysine, Quinolone
Document Summary
Gc base pair ( put the ribose on the same side ) Purine base [6 ring, 2 nitrogens + 5 ring, 2 nitrogen] / a = only has 1 amino group. / g = has amino, extra hydrogen, and a double o. Sugar = d-ribose (5 carbon sugar, the numbers get primes) The prime helps distinguish them from # on base. Base connects to sugar via a b-n-glycosidic bond (base is pointing up) Nucleotides = nucleoside + phosphate monosaccharide, most commonly either the 3" or the 5"-oh (default) A nucleoside in which a molecule of phosphoric acid is esterified with an -oh of the camp = 3"-5"-cyclic adenosine monophosphate (cyclic adenosine monophosphate) Used in many biological processes in cell signaling (intracellular signal transduction) as an important 2nd messenger. By looking at the structure, you should know it is a nucleoside analog because the lack of. Zidovudine is a nucleoside analog reverse transcriptase inhibitor (nrti) used to treat hiv: phosphate group.
