BIOL1300 Chapter Notes -Brainstem

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Blood brain barrier the fact that the capillary structure and space between blood compartment and brain tissue compartment is sealed off so some of the molecules in the blood that might filter through remain in the blood and do not reach the brain tissue capillaries consist of one cell layer, in order for materials to go through they have to go through capillary walls or cells, endothelial cells connected by very tight junctions basement membrane glycoproteins physical barrier astrocytes have feet like projections that land on the capillaries and prevent movement of molecules (physical barrier) certain nutrients, chemicals, drugs, cannot move from blood to the brain (some things we night want to get to the brain have more difficulty: dopamine neurotransmitter naturally found in the brain not uniformly present, some areas of the brain where it is absent (hypothalamus, brain stem) vomiting in part facilitated by that whatever needs to be eliminated is detected.

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