CAS BI 325 Chapter Notes - Chapter 19: Generalised Tonic-Clonic Seizure, Partial Seizure, Cerebral Cortex
2 Jan 2018
School
Department
Course
Professor
Document Summary
(2) can share or distribute timing function among themselves by mutually exciting. Sleep-related rhythm = way to disconnect the cortex from sensory input. Awake cortex rhythms = used to coordinate activity b/w . Involves entire cerebral cortex of both hemispheres. Both: neurons w/in affected area fire w synchrony that doesn"t occur during normal behavior. Causes na channel to remain open longer allows more na current to enter . Drugs that block gaba receptors = potent . Withdrawal of chronic depressant drugs like alcohol or barbiturates can trigger seizures. Drugs to suppress seizures: critical for synth/transport, or proteins involved in its release. Mediated by gaba by affecting its receptors, enzymes. Prolonging inhibitory actions of gaba (i. e. barbiturates, benzodiazepines) Decrease tendency for certain neurons to fire ap @ high frequencies (i. e. behavioral features of seizures dependent on which neurons are involved and the phenytoin, carbamazepine) pattern of their activity.
