BIOL 202 Chapter Notes - Chapter 19: Fibrinogen, Gram-Negative Bacteria, Streptokinase
Document Summary
Establishment of infection and disease; host and pathogen: signs: traits detected by an observer (such as a physician) in response to a pattern of suspected disease, symptoms: signs as observed as the patient. 2: syndrome: the collection of signs and symptoms together as a common pattern of disease. Breaching host barriers: some pathogens do not needs to pierce cell tissues; by adhering to the surface, they can produce toxins that cause disease, virulence, however, is heavily dependent upon cell penetration, this is called invasiveness. Injected directly into the host cell: cytotoxins: kill cells. Produce cells that lyse cells: neurotoxins: interfere with nerve transmission; blocks relaxation pathway to cause tetanus, enterotoxins: affect the intestinal tract. Pathogens must be able to leave the host to spread disease: portal of exit: the way pathogens exit the host. Epidemiologists have several terms that apply to the infectious disease.