BIOL 142 Chapter Notes - Chapter 19.5-19.6: Rna Interference, Alternative Splicing, Chromatin

• School: Emory University
• Department: Biology
• Course: BIOL 142
• Professor: Patrick Cafferty

Document Summary

19. 5 how does gene expression compare in bacteria and. Summary: regulating gene expression in bacteria and eukaryotes. Extensive packaging of dna: remodeling not a major issue in regulating gene expression, chromatin must be decondensed for transcription to begin. Transcription: positive and negative control, positive and negative control by by regulatory proteins that act at sites close to the promoter. Sigma interacts with promoter regulatory proteins that act at sites close and far from the promoter. Large set of transcription factors interact with the core promoter and many regulatory sequences. Rna processing rare mrna stability: rarely used for control, mediator required. Extensive processing: alternative splicing of introns: commonly used: rna interference limits life span of translation rate of many mrnas. Translation: regulatory proteins bind to mrnas and ribosomes and affect translation rate, regulatory proteins bind to mrnas and ribosomes and affect translation rate.