BIOL 301 Chapter Notes - Chapter 6: Enzyme Catalysis, Binding Energy, Weak Interaction
Document Summary
Most enzymes are proteins (exception of small group of catalytic rna molecules) If enzyme is denatured or dissociated into subunits, catalytic activity lost. Some enzymes dont require chemical group other than their aa residues. Some require cofactor - 1+ inorganic ions. Some require complex organic molecule called coenzyme. Act as transient carriers of specific functional groups. Coenzyme or metal ion that is tightly bound to enzyme proteins is called prosthetic group complete , catalytically active enzyme with its bound coenzyme is called holoenzyme. Protein part of holoenzyme is called apoenzyme or apoprotein. Some enzymes are modified covalently by phosphorylation, glycosylation, Enzymes are classified by the reactions they catalyze and other processes. All enzymes have formal e. c. numbers and names, and most have trivial names. A simple enzymatic reaction might be written. E + s es ep e + p. E, s and p represent the enzyme, substrate, and product.
