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Chapter 20

MCB 3020L Chapter Notes - Chapter 20: Lysogenic Cycle, Protoplasm, Capsid


Department
Microbiology
Course Code
MCB 3020L
Professor
Scheurle Daniela
Chapter
20

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Viruses (part 2)
o Temperate Viruses tend to undergo a lysogenic pathway in order to multiply
the number of viral particle present:
When the host cell reproduced it also reproduces the viral nucleic
acids and the daughter cells contain the copies of the viral genetic
material
The viral infection will stay that way until conditions are deemed
favorable for their release, when they will switch to a virulent pathway
(lytic pathway)
At which point they will switch to a lytic pathway, which will then
initiate the mass replication and the release via the lysing of different
cells
STEPS: Attachment, Penetration, Protein Synthesis, Assembly, Release
Bacteriophages: viruses that are specific to bacterial hosts
T-even bacteriophages: somewhat more complex structure
o Capsid: contains the nucleic material
o Proteins on the tail fibers are specific for receptors on the surface of a
bacterium
o Virus particles attaches to the cell surface with the viral pin, which can aid
attachment to a specific type of host cell
o Nucleic acids are then “pumped” from the capsid, through the tail sheath and
pin, and into the protoplasm of the host, where they will eventually hijack the
cellular machinery of the host cell
In order to observe a viral infection in a cultured form, we must provide the virus
with a suitable host that it can live within
Viral infections can be viewed on an agar plate
o Infection will initiate
o Lytic pathway: patches (plaques) of dead bacteria
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