BISC 2539 Chapter Notes - Chapter 2: Proband, Hypophosphatemia, Haemophilia

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Initial lines (i. e. green and yellow seeds) were parental generation (p: progeny generation (all yellow) is first filial generation (f1) 2: progeny from crossing f1 is second filial generation (f2) 3:1 yellow:green, mendel selfed plants grown from f2 seeds green ones bear only green peas, yellow ones bear. 2. 2 the chromosomal basis of single gene inheritance patterns: gene pairs are located on chromosome pairs actually it is members of chromosome that segregate, carrying genes with them. Structural differences between alleles at the molecular level: alleles are genes that are identical in most of sequence, differ only at 1 or several nucleotides, different versions of the same gene. If nucleotide of an allele is changed, a mutant allele is produced (can be anywhere in sequence) Molecular aspects of gene transmission: replication of alleles during s phase, dna molecule is replicated accurately.

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