BISC 3221 Chapter Notes - Chapter 25: Sternocleidomastoid Muscle, Chyme, Vagus Nerve

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Chapter 25: The Digestive System
• Digestive system = digestive tract + accessory organs
o Tract: oral cavity + esophagus + stomach + small intestine + large intestine
o Accessory: teeth + tongue + salivary glands + liver + pancreas
• Functions
o Ingestion: food and liquids enter digestive tract at mouth
o Mechanical processing: squashing with tongue, crushing with teeth, movement in
stomach
o Digestion: chemical and enzymatic breakdown of sugars/lipids/proteins into smaller
molecules
o Secretion: secrete acids, enzymes, buffers by tract or accessory organs
o Absorption: movement of organic molecules, electrolytes, vitamins, water across
digestive epithelium and into interstitial fluid
o Excretion: waste products secreted into digestive tracts
o Compaction: dehydration of indigestible materials/wastes before defecation of feces
• Lining of tract protects against corrosive effects of acids/enzymes, mechanical stresses, pathogens
swallowed/living in digestive tract
25.1 An Overview of the Digestive System
Histological Organization of the Digestive Tract
• Major layers: mucosa, submucosa, muscularis externa, serosa
• Variations are related to specific organ/region
• The Mucosa
o Inner lining, example of mucous membrane; loose connective tissue covered by
epithelium moistened by secretions
o Mucosal epithelium can be stratified (mouth) or simple (small intestine) (depends on
location)
o Mucosa of tract is organized in folds (plicae) that increase surface area for absorption; in
some areas they are permanent, in others they disappear as lumen fills
o Lamina propria: areolar tissue under epithelium; contains blood vessels, sensory nerve
endings, lymphatic vessels, smooth muscle fibers, areas of lymphatic tissue (part of
MALT)
o Muscularis Mucosae
▪ Band of smooth muscle and elastic fibers external to lamina propria
▪ Inner circular layer, outer longitudinal layer
• The Submucosa
o Dense, irregular CT outside muscularis mucosae
o Contains large blood vessels and lymphatics, exocrine glands that secrete
enzymes/buffers
o Submucosal plexus: network of nerve fibers/neuron bodies along outer margin;
innervates mucosa; contains sensory neurons, parasymp. ganglia, symp. ganglia
• The Muscularis Externa
o Surround submucosa, dominated by smooth muscle; inner circular, outer longitudinal
o Plays important role in mechanical processing, moving material through tract
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o Myenteric plexus: network of parasymp. ganglia and symp. postganglionic fibers
between 2 muscle layers; coordinate movements of 2 layers
o Forms sphincters at certain points along tracts; thickened areas of circular smooth muscle
• The Serosa
o Outer serous membrane
o NONE at pharynx, esophagus, rectum; instead adventitia (thick, fibrous sheet)
Muscularis Layers and the Movement of Digestive Materials
• Smooth muscle, nonstriated, involuntary, surrounded by CT, most have no motor innervation,
arranged in sheets, gap junctions electrically connect adjacent cells; when on contracts, the
contraction spreads like a wave throughout tissue
• Can contract in response to neurons, chemicals, hormones, concentrations of O2 or CO2, physical
factors (stretching/irritation)
• Plasticity: ability for muscle cell to adapt to stretched length and retain ability to contract on
demand
• Pacemaker cells: undergo spontaneous depolarization, causing contractions that lead to peristalsis
and segmentation; maintains rhythmic cycles in smooth muscle
• Peristalsis
o Waves of muscular contractions that move a bolus along length of tract
o Peristaltic wave: circular muscles contract behind digestive contents, then longitudinal
muscles contract, shortening adjacent segments, then circular contraction pushes bolus
• Segmentation
o Occurs in small intestine and large intestine
o Movements churn and fragment digestive materials, don’t produce net movement in a
direction
• Segmentation and peristalsis can be triggered by pacemaker cells, hormones, chemicals, physical
stimulation
• Peristalsis can be triggered by afferent and efferent fibers in glossopharyngeal, vagus, pelvic
nerves
• Myenteric reflexes: short reflexes that don’t involve CNS; can control local contractions
• Long reflexes: involve CNS interneurons and motor neurons; control large scale peristaltic waves
that move stuff from one region of tract to another
The Peritoneum
• Visceral peritoneum (serosa) is continuous with parietal peritoneum (lines inner body wall)
• Intraperitoneal organs: in peritoneal cavity, covered on all sides by visceral peritoneum (stomach,
liver, ileum)
• Retroperitoneal organs: covered by visceral peritoneum on anterior surface, organ lies outside
peritoneal cavity (kidneys, ureters, abdominal aorta)
• Secondary retroperitoneal organs: form as intraperitoneal but become retroperitoneal (pancreas,
duodenum)
• Peritoneum produces peritoneal fluid that lubricate surfaces
• Mesenteries
o Fused double sheets of peritoneal membrane
o Stabilize relative positions of organs, prevent entanglement of intestines
Document Summary
Chapter 25: the digestive system: digestive system = digestive tract + accessory organs, tract: oral cavity + esophagus + stomach + small intestine + large intestine, accessory: teeth + tongue + salivary glands + liver + pancreas, functions. Histological organization of the digestive tract: major layers: mucosa, submucosa, muscularis externa, serosa, variations are related to specific organ/region, the mucosa. Malt: muscularis mucosae, band of smooth muscle and elastic fibers external to lamina propria. The peritoneum: visceral peritoneum (serosa) is continuous with parietal peritoneum (lines inner body wall) Intrinsic tongue muscles + extrinsic tongue muscles are under control of hypoglossal nerve (xii: extrinsic = hyoglossus, styloglossus, genioglossus, palatoglossus; perform gross movements of tonue. Intrinsic muscles alter shape of tongue, help in precise movements. Regulation of the salivary glands: controlled by autonomic nervous system, salivary glands all have symp and parasymp innervation, para stimulation accelerations rate of secretion, symp results in less secretion.