BIOL 3450 Chapter 2: Chapter 2 – Chemical Foundations

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18 Feb 2019
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Chapter 2 chemical foundations: covalent bond ~ when two atoms share single pair of electrons, noncovalent interactions ~ weak attractive forces. Ionic interactions are attractions between oppositely charged ions. Ionic interactions ~ result from attraction between positively charged ion (cation) and negatively charged ion (anion: energy required to break ionic interactions depends on distance between ions and electrical properties of environment of ions. Increasing concentrations of salts in solution of biological molecules can weaken and even disrupt ionic interactions holding biomolecules together used to separate complex mixtures of interacting molecules like proteins into individual, pure components. Hydrogen bonds are noncovalent interactions that determine the water solubility of uncharged. Molecules: hydrogen bond ~ interaction of partially positively charged hydrogen atom in dipole, like water, with unpaired electrons from another atom, either in same or different molecule. Molecular complementarity due to noncovalent interactions leads to lock and key fit dissolve in nonpolar solvents like hexane.

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