BMS 250 Chapter Notes - Chapter 7: Thyroid, Collagen, Calcifediol
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In this process, osteoblasts in the inner cellular layer of the periosteum produce and deposit bone matrix within layers parallel to the surface, called external circumferential lamellae. These lamellae are analogous to tree rings: as they increase in number, the structure increases in diameter. Thus, the bone becomes wider as new bone is laid down at its periphery. At this new bone is being laid down, osteoclasts along the medullary cavity resorb bone matrix, creating an expanding medullary cavity. The combined effects of bone growth at the periphery and bone resorption within the medullary cavity transform an infant bone into a larger version called an adult bone. Ii: even when adult bone size has been reached, the bone continues to renew and reshape itself throughout a person"s lifetime. This constant, dynamic process of continual addition of new bone tissue(cid:345)bone deposition(cid:346) and removal of old bone tissue(cid:345)bone resorption(cid:346) is a process called bone remodeling.