NUR 239 Chapter Notes - Chapter 8: Lymphokine, Cytotoxicity, Anaphylaxis
23 Jun 2018
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Porth Chapter 15 – Mechanisms of Infectious Disease
Define the following terms:
Innate Immunity-
physical, cellular, chemical, and molecular defenses that are
ready for activation. Provide rapid initial protection against
infectious Microbes.
Adaptive Immunity-
component of the immune system which protects the body
from potentially harmful foreign agents. It is specific protection
established after exposure to an antigen (active immunity) or
through the transfer of antibodies against the antigen (Passive
immunity).
Antibodies-
Are foreign bodies and are recognized by receptors on the immune cells
and by secreted proteins made in response to the antigen
Antigens
Foreign substances that start and immune response
Active immunity
Acquired through immunization or actually having a disease
Passive immunity
Is immunity transferred from another source
Self-regulation
An essential property of the immune system.
Tolerance
The ability of the immune system to be nonreactive to self-antigens while
producing immunity to foreign agents
Key Learning Objectives - Answer the follow questions (Porth Chapter 15)
List the components of the innate immune system and briefly describe each.
Skin and mucus membranes, phagocytic leukocytes mainly neutrophils
and macrophages), specialized lymphocytes (the natural killer cells), and several
plasma proteins, including the proteins of the complement system.
It is able to distinguish between nonself and self and is able to recognize
and react against various classes of microbial agents.
Describe the innate immune system response
Rapid, usually within minutes to hours, and prevents the establishment of
infection and deeper tissue penetration of microorganisms.
Innate immunity is the first line of defense against ____________.
Microbes
Compare/contrast the innate and adaptive immune systems.
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Document Summary
Porth chapter 15 mechanisms of infectious disease. Innate immunity- physical, cellular, chemical, and molecular defenses that are ready for activation. Adaptive immunity- component of the immune system which protects the body from potentially harmful foreign agents. It is specific protection established after exposure to an antigen (active immunity) or through the transfer of antibodies against the antigen (passive immunity). Are foreign bodies and are recognized by receptors on the immune cells and by secreted proteins made in response to the antigen. Acquired through immunization or actually having a disease. The ability of the immune system to be nonreactive to self-antigens while producing immunity to foreign agents. Key learning objectives - answer the follow questions (porth chapter 15) List the components of the innate immune system and briefly describe each. Skin and mucus membranes, phagocytic leukocytes mainly neutrophils and macrophages), specialized lymphocytes (the natural killer cells), and several plasma proteins, including the proteins of the complement system.
